Dr. Wandera Bonnie
Position : Makerere University College of Health Sciences
Dr Wandera Bonnie is a Ugandan registred at Makerere University and holds a Bachelor of Medicine and Bachelor of Surgery degree from Makerere University and a Masters degree in Epidemiology and Biostatistics from Case Western Reserve University.
Previously, he worked on a research project to evaluate sexual behaviours of HIV infected persons receiving antiretroviral therapy for up to 3 years, at the Infectious Diseases Institute clinic and has 7 years experience in clinical care and research with major emphasis on Infectious diseases associated with HIV/AIDS.
This PhD fellowship comes in handy in his quest to develop an interdisciplinary collaborative research team of various Ugandan professional fields/faculties from health scientists, psychologists, sociologists, and social workers involved in alcohol research to evaluate an alcohol intervention program among PLWHA in Uganda
Background: Although both HIV and alcohol use are highly prevalent in sub-Saharan Africa (SSA), few interventions have been tested in SSA. We tested the efficacy of a brief motivational intervention (BMI) for reducing alcohol use among PLWHA.
Methods: PLWHA attending an outpatient HIV clinic in Kampala were screened for self-reported alcohol use using the alcohol disorders identification test-Consumption component (AUDIT-C). Subjects scoring e”3 points were randomized to receive either the standardized positive prevention counseling (SPPP) or an alcohol BMI counseling and followed up at 3 and 6 months post intervention. Mean AUDIT-C scores were compared over time by treatment arm using linear mixed models
Results: Of the 883 subjects screened for alcohol use, 340 subjects (65% were male) scored e”3 on AUDIT-C and were randomized to the two arms. Their median age and CD4 cell counts were 39 (32-46) years, 381(274-507) cells/mm3 respectively. The mean AUDIT-C scores were 6.3(2.3) and 6.8(2.3) for control and BMI arms at baseline and respectively declined to a mean of 3.4(3.0) and 3.9(3.0) at month six. The adjusted mean BMI arm effect was 0.37(p=0.1), time effect
-0.78(p < 0.0001), and arm by time interaction of -0.03(p=0.9).
Conclusion: Over the six months, addition of a BMI component did not result in significantly greater declines in alcohol use by AUDIT-C. Routine clinical visits for PLWHA should continue with provision of a structured positive prevention counseling package that includes reduction of alcohol use. Detailed analyses are ongoing.