Dr. Joel Ltilitan Barguli
A Lecturer at the Department of Biochemistry of Jomo Kenyatta University of Agriculture and Technology (Kenya). Joel’s broad research interest focuses on the understanding of transmission dynamics of neglected tropical diseases by studying the interactions between insect vectors, disease pathogens and mammalian hosts. In the last ten years, during his MSc and PhD research studies based at icipe (Nairobi), Joel has been studying the biology of tsetse fly and the African trypanosomes. Trypanosomes are transmitted by the tsetse fly and cause severe diseases in man and livestock.Joel completed his PhD at the University of Wuerzburg (Germany) under the mentorship of Prof.Dr. Markus Engstler, Dr. Daniel Masiga, and Dr. Francis McOdimba. He studied the motility of African trypanosomes, as motility is necessary for survival of these parasites.
His study demonstrated, for the first time, the reasons for variations in swimming patterns, speeds, and host-tissue distribution of different species of animal African trypanosomes. Animal trypanosomiasis is a neglected tropical disease that causes huge setback to livestock production, hence contributing to poverty. Driven by curiosity, I recently collected some little studied blood-feeding hippoboscids from camels in northern Kenya in order to study their role in transmission of trypanosomes. More than 25% of the flies were infected with trypanosomes, and when these flies fed on experimental rabbits, these animals acquired trypanosome infection suggesting that hippoboscids could transmit trypanosomes. These preliminary findings imply that hippoboscids could be important vectors of animal trypanosomiasis.
The award of THRiVE Postdoctoral fellowship is very essential for the success of this research study whose findings will provide information on vectors of animal trypanosomes in northern Kenya and contribute to disease control. THRiVE-2 fellowship has enabled Joel initiate research collaborations with Prof. Mark Carrington (University of Cambridge) and Dr. Daniel Masiga (icipe, Nairobi). Both Mark and Dan have huge research experience of over 25 years in the field of African trypanosomiasis, and will provide mentorship during the studies.